US-KL alone can be used to determine whether there is risk of rapid disease progression in ADPKD.*1
MRI is the recommended imaging modality for the most accurate and reproducible measurement of kidney length, kidney cyst burden, and TKV. As such, MRI/CT-calculated TKV is a strong predictor of future renal insufficiency in ADPKD. However, US-measured KL is a useful surrogate when MRI/CT-calculated TKV is not feasible.1
US-measured predictor of rapid progression† KL > 16.5 cm in patients less than 45 years old
†when rapid progression is defined as CKD stage 3 development within 8 years1,2
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